Anticoagulant activities of acidic glycosaminoglycans
نویسندگان
چکیده
منابع مشابه
Structure and anticoagulant properties of sulfated glycosaminoglycans from primitive Chordates.
Dermatan sulfates and heparin, similar to the mammalian glycosaminoglycans, but with differences in the degree and position of sulfation were previously isolated from the body of the ascidian Styela plicata and Ascidia nigra. These differences produce profound effects on their anticoagulant properties. S. plicata dermatan sulfate composed by 2-O-sulfated alpha-L-iduronic acid and 4-O-sulfated N...
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Almost monodisperse heparin fractions (Rw/%r < 1.1) were obtained by gel filtration of a commercial heparin. These fractions were assayed for anticoagulant activity (thrombin times and APTT), chromogenic anti-factor Xa activity, inhibitory activity for the human classical complement pathway, carboxyl group content and total sulfate content. Linear relationships were observed between the molecul...
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ژورنال
عنوان ژورنال: Blood & Vessel
سال: 1979
ISSN: 0386-9717,1884-2372
DOI: 10.2491/jjsth1970.10.68